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Leon Edwards and his thousands of hometown supporters welcome Kamaru Usman to their colosseum on Saturday night. Usman enters enemy territory at the O2 Arena in London, England in pursuit of the UFC welterweight championship. 

The fight game produces profound changes in the blink of an eye. In August, Usman was 56 seconds away from tying the all-time UFC win streak record and sweeping Edwards 2-0 in their series. Improbably, Edwards lulled Usman into a trap that changed the landscape of the welterweight division. Edwards, clearly down on the scorecards, uncorked a brilliant head kick that laid out Usman for good. Edwards brought a rare UFC championship home to England and must defend it against his greatest rival in their trilogy fight.

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The undercard fills out with some fun battles that could produce fireworks. Look no further than the co-main event when “The Highlight” Justin Gaethje returns. The perennial lightweight contender is back as he looks to turn away the next rising contender in the division in the form of Rafael Fiziev. Gaethje hinted at the possibility of engaging with his wrestling background for the first time in his UFC career this week.

Plus, submission specialist Gunnar Nelson is back in action when he takes on brawling brute Bryan Barberena. Casey O’Neill is back after a nasty knee injury when she takes on veteran Jennifer Maia at flyweight. And the main card opens with an important bout at middleweight when former title challenger Marvin Vettori takes on rising contender Roman Dolidze.

Below is all the information you need to catch UFC 286 on Saturday night. 

How to watch UFC 286 prelims

Date: March 18  | Location: O2 Arena — London
Time: 3 p.m. ET (1 p.m. ET for early prelims)
Channel: ESPN 2 | Stream: fuboTV (Try for free)

How to watch UFC 286 main card

Date: March 18  | Location: O2 Arena — London
Time: 5 p.m. ET
Stream: ESPN+ PPV | Price: $79.99

Now, here’s a look at the UFC 286 main fight card and betting odds via Caesars Sportsbook.

UFC 286 main card, odds

Kamaru Usman -240 Leon Edwards (c) +200 Welterweight title
Rafael Fiziev -230 Justin Gaethje +190 Lightweights
Gunnar Nelson -370 Bryan Barberena +290 Welterweights
Casey O’Neill -175 Jennifer Maia +150 Women’s flyweights
Marvin Vettori -280 Roman Dolidze +230 Middleweights

Who wins Edwards vs. Usman at UFC 286? And how exactly does each fight end? Visit SportsLine now to get detailed picks on every fight at UFC 286, all from the MMA expert who profited more than $6,200 in 2022, and find out.